GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRCA | cis | rs13191362 | 1 | rs13214516 | chr6:163121583 | PACRG | chr6:163148164-163736523:+ | 0.24 | 4.15 | 3.57E-5 | Body mass index |
| BRCA | cis | rs1056667 | 1 | rs1321479 | chr6:26501897 | BTN2A3 | chr6:26422317-26431927:+ | -0.15 | -5.04 | 5.37E-7 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321479 | chr6:26501897 | C6orf41 | chr6:26924772-26991752:+ | 0.12 | 3.73 | 0.000199 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321479 | chr6:26501897 | ZNF322A | chr6:26634612-26659963:- | 0.11 | 4.18 | 3.09E-5 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321480 | chr6:26532742 | BTN2A3 | chr6:26422317-26431927:+ | 0.16 | 5.48 | 5.33E-8 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321480 | chr6:26532742 | C6orf41 | chr6:26924772-26991752:+ | -0.12 | -3.63 | 0.000299 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321480 | chr6:26532742 | ZNF322A | chr6:26634612-26659963:- | -0.1 | -3.43 | 0.000629 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321481 | chr6:26538210 | BTN2A3 | chr6:26422317-26431927:+ | 0.16 | 5.48 | 5.38E-8 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321481 | chr6:26538210 | C6orf41 | chr6:26924772-26991752:+ | -0.12 | -3.75 | 0.00019 | Educational attainment |
| BRCA | cis | rs1056667 | 1 | rs1321481 | chr6:26538210 | ZNF322A | chr6:26634612-26659963:- | -0.1 | -3.72 | 0.000207 | Educational attainment |
| BRCA | cis | rs13215566 | 1 | rs13215017 | chr6:89918264 | GABRR1 | chr6:89887223-89927496:- | 0.17 | 3.44 | 0.000595 | Spherical equivalent (joint main effects and education interaction) |
| BRCA | cis | rs13191362 | 1 | rs13215491 | chr6:163010325 | PACRG | chr6:163148164-163736523:+ | 0.23 | 4.37 | 1.36E-5 | Body mass index |
| BRCA | cis | rs13215566 | 1 | rs13215566 | chr6:89918638 | MDN1 | chr6:90353231-90529442:- | 0.1 | 3.46 | 0.000564 | Spherical equivalent (joint main effects and education interaction) |
| BRCA | cis | rs1577917 | 1 | rs13217384 | chr6:86720000 | SNHG5 | chr6:86386726-86388451:- | -0.6 | -18.92 | 4.69E-69 | Response to antipsychotic treatment |
| BRCA | cis | rs9387478 | 1 | rs1321798 | chr6:117731192 | ROS1 | chr6:117609530-117747018:- | -0.14 | -4.85 | 1.45E-6 | Lung cancer |